Awards

Gene Codes has been recognized by many different organizations around the world.

The International Society for Computational Biology recognizes Howard Cash and Gene Codes Forensics for the unique application of computational biology to help with disaster victim identification. ISCB President Michael Gribskov called Gene Codes' contribution "unique, valuable, and beyond the limit of what could be expected".
Ann Arbor IT Zone recognizes Gene Codes Corporation with the Indestructible Award for Growth and Achievement.
Gene Codes is awarded the Merlanti Prize for Best Practices in Business Ethics.
Genome Technology makes Howard Cash Person of the Year in their All-Star Awards.
Gene Codes Corporation is named one of the Future 50 of Greater Detroit: "In recognition of your outstanding contribution to Metropolitan Detroit through sales and employment growth."
Ernst & Young and The New Enterprise Forum name Howard Cash, President, CEO and founder of Gene Codes, Entrepreneur of the Year.
Gene Codes wins the Washtenaw County Fast Track Award.
Sequencher receives the Best DNA Sequence Assembly Product from the Biotechnology Software & Internet Journal.
Gene Codes receives Michigan Leading Edge Technology Award in the biotechnology category. The award recognizes innovations introduced with Sequencher version 3.0, giving special mention to enhancements that allowed increased process automation.
Gene Codes receives the Best Presentation of the Year award by the Michigan Branch of the New Enterprise Forum: "In recognition of an innovative business venture which has helped make Gene Codes Corporation a model entrepreneurial firm."

Questions

We would love to hear from you! Please give us a call at 734-769-7249 or fill out our contact form here.

"The most popular request I receive in the DNA core lab is: find the good clone among this group of 'candidate' minipreps. Alignment of ABI data files against a 'reference' sequence (template file) quickly eliminates defectives by showing not only base changes but the consequences to the protein translation. The second most popular request is: validate this new maxiprep so it can be given to ... or used for ... or expressed in ... Rapid assembly and editing of total plasmid sequence and then comparison to the reference file on record is all done in Sequencher. The third most popular request is: compare this library of (protein improvement) mutants and tell me which ones have protein changes. This is done by alignment in Sequencher and then formatting the Summary view to display the resulting changes in protein translation. For my own projects, I use Sequencher as a very general multiple-alignment sequence editor. Most recently, I've been using it to make comparisons of genes retrieved from the databases for cross-species cDNA cloning. Showing regions of homology at the protein level and then having the colinear DNA sequence presented in the same view (Summary window) helps find regions suitable for primer design. Turning on the Matching Bases/Residues as Dashes quickly shows regions of homology and divergence. I design primers to either or both depending on the project. "

Dean Regier, Research Scientist DNA core laboratories

"Whether it has been for building contigs in the search for novel causative mutations, verifying proper vector construction, or simply aligning large numbers of samples for typing of a single SNP, it has been an invaluable tool. With the advent of next generation sequencing technologies, it becomes even more necessary to have trustworthy, user-friendly software. "

Rob Loechel, Chief Scientific Officer, Vetgen, L.L.C.

"After using Sequencher for years as a grad student, I was forced to switch to MacVector as a postdoc in a new lab. Sequencher is so much easier to use than MacVector and has such a superior interface that I used the demo version of Sequencher for months rather than the lab copy of MacVector. Sequencher feels as though it is written by biologists that can write software, rather than programmers attempting to write biological software. Any life scientist who has spent time pulling their hair out over non-intuitive software will greatly appreciate this distinction. "

Dave Parker, University Of Michigan Cell And Developmental Biology

" Sequencher 4.10.1 contains a new feature that keeps track of protein and cDNA numbering in DNA assemblies. This ability greatly simplifies the task of comparing your experimental data to a genomic DNA reference when looking for mutations or other changes. This feature alone reinforces Sequencher as one of the premier tools for sequence analysis. "

David Adams, M.D Ph.D Clinical Investigator and Sequencher 4.10.1 beta tester

"Thank you for sending the demo version of Sequencher. This seems to be wonderful software for phylogenetic and mutation studies. It clearly indicates start and stop codons in DNA sequences. Sequencher is easy to use and allowed us to quickly align sequences from various individuals. This software is very user friendly, and the instruction manual is very informative. The contig assembly tool is quite amazing in its speedy and time saving functions, which are the requirements for researchers in the biochemical field. I really got exited by running this software. "

Dr V.R.C. Murty, Department of Chemical Engineering Manipal Institute of Technology

"I have been involved in DNA sequencing projects since I got my masters degree in bioinformatics in 2002. The programs I used for sequences analysis included Vector NTI from Invitrogen, PhredPhrap, Lasergene from DNAStar, and Sequencher. Sequencher is my favorite program not only because of its powerful SNP analysis functions but also because it is very easy to use and user friendly. I would like to recommend Sequencher to people who are doing SNP research projects and/or responsible for training students and colleagues who are going to do genotyping work. "

Zongying Xi, MD/MS, Department of Pharmaceutical Sciences St Jude Children's Research Hospital

"I just wanted to let you know how much the modifications to Sequencher have assisted in our data flow. The time saving has been amazing. Assembling our data has taken third the time it usually does, and has allowed for the smoothest assembly of our data for a vaccine selection that I can remember. Additionally noteworthy as we have produced more data for this selection than ever before. Please let your programmers know that the work that they have done has truly helped and thank them for their efforts. "

An Associate Research Fellow, US Centers for Disease Control and Prevention

"Sequencher is not just the best sequence analysis program I have used; it is one of the best pieces of software I have used. Period. It is intuitive; it does exactly what I want it to do in pretty much the way I would expect it to work. "

Wilson Clements, Ph.D., University of California, San Diego

"I am involved in resequencing projects for disease association studies. Sequencher was of tremendous help to me in these projects for- discovery of SNPs, detection of known SNPs, intronic/exonic SNPs & amino acid changing SNPs. I have been using it for sequence analysis of ABI data files since 2000. It is easy to operate and user friendly. It was a pleasure to be involved in the beta test program for version 4.6. What I liked in this new version is assembly function & variance table. Assemble to reference by defining assembly parameters using advance expression feature is very useful, it saves a lot of time and sequences can be assembled by defining feature of your choice e.g. sample ID, primer ID, or well position etc. Technical Support group at the Gene Codes Corporation has been very receptive to the idea of introducing variance table. With this feature it is now possible to export genotypes. Using this feature I am not only able to export whole table but also selected few columns using “export selected” option button. "

Manjula Maheshwari, Human Genome Sequencing Center Baylor College of Medicine Houston, Texas

"Sequencher, from Gene Codes of Ann Arbor, Mich., is possibly today's most popular software for DNA Sequencing. "

Steven D. Buckingham, Sequence Analysis Software Update, The Scientist, December 20, 2004

About Gene Codes

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